Rothia dentocariosa sepsis in a pediatric renal transplant recipient having post-transplant lymphoproliferative disorders

Pediatr Transplant. 2006 May;10(3):377-9. doi: 10.1111/j.1399-3046.2005.00472.x.

Abstract

Background: Rothia dentocariosa (RD) is a Gram-positive rod that colonizes the human oral cavity and can cause infective endocarditis.

Result: We report on a six-yr-old boy who underwent renal transplantation for polycystic kidney disease at the age of eight months. He developed post-transplant lymphoproliferative disorders after four yr and progressive graft failure. Following chemotherapy, the patient presented with neutropenia and sepsis. RD was isolated from blood and treatment with piperacillin/tazobactam was initiated; however, the child died because of multiorgan failure.

Discussion: To the best of our knowledge, this is the first case of RD sepsis in a pediatric solid organ transplant recipient.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Fatal Outcome
  • Graft Rejection
  • Humans
  • Immunosuppressive Agents / pharmacology
  • Kidney Transplantation / adverse effects*
  • Kidney Transplantation / methods*
  • Lymphoproliferative Disorders / complications*
  • Lymphoproliferative Disorders / microbiology*
  • Male
  • Nocardia / metabolism*
  • Polycystic Kidney Diseases / therapy
  • Sepsis / etiology*
  • Sepsis / microbiology*
  • Treatment Outcome

Substances

  • Immunosuppressive Agents