Abstract
We used pulsed-field gel electrophoresis analysis and genotyping to compare clinical isolates of Bordetella pertussis recovered since the early 1990s in Finland and France, 2 countries with similar histories of long-term mass vaccination with whole-cell pertussis vaccines. Isolates from both countries were similar genetically but varied temporally.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Bacterial Outer Membrane Proteins / chemistry
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Bacterial Outer Membrane Proteins / genetics
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Bordetella pertussis / classification*
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Bordetella pertussis / genetics
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Bordetella pertussis / immunology
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DNA, Bacterial / chemistry
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DNA, Bacterial / genetics
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Diphtheria-Tetanus-Pertussis Vaccine / immunology*
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Electrophoresis, Gel, Pulsed-Field
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Fimbriae Proteins / chemistry
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Fimbriae Proteins / genetics
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Finland / epidemiology
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France / epidemiology
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Genetic Variation
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Humans
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Pertussis Toxin / chemistry
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Pertussis Toxin / genetics
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Virulence Factors, Bordetella / chemistry
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Virulence Factors, Bordetella / genetics
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Whooping Cough / epidemiology
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Whooping Cough / immunology
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Whooping Cough / microbiology*
Substances
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Bacterial Outer Membrane Proteins
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DNA, Bacterial
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Diphtheria-Tetanus-Pertussis Vaccine
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Virulence Factors, Bordetella
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pertussis toxin, S1 subunit
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Fimbriae Proteins
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pertactin
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Pertussis Toxin