Origins of the T(H)1-T(H)2 model: a personal perspective

Nat Immunol. 2006 Jun;7(6):539-41. doi: 10.1038/ni0606-539.

Abstract

Robert L. Coffman recounts how his work on immunoglobulin E regulation along with data from Tim Mosmann on the functional heterogeneity of T cell clones led to the T helper type 1-T helper type 2 hypothesis.

Publication types

  • Biography
  • Historical Article

MeSH terms

  • Allergy and Immunology / history*
  • Animals
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Models, Immunological
  • Th1 Cells / immunology*
  • Th2 Cells / immunology*

Personal name as subject

  • Robert L Coffman