GenePro: a Cytoscape plug-in for advanced visualization and analysis of interaction networks

Bioinformatics. 2006 Sep 1;22(17):2178-9. doi: 10.1093/bioinformatics/btl356.

Abstract

Motivation: Analyzing the networks of interactions between genes and proteins has become a central theme in systems biology. Versatile software tools for interactively displaying and analyzing these networks are therefore very much in demand. The public-domain open software environment Cytoscape has been developed with the goal of facilitating the design and development of such software tools by the scientific community.

Results: We present GenePro, a plugin to Cytoscape featuring a set of versatile tools that greatly facilitates the visualization and analysis of protein networks derived from high-throughput interactions data and the validation of various methods for parsing these networks into meaningful functional modules.

Availability: The GenePro plugin is available at the website http://genepro.ccb.sickkids.ca.

MeSH terms

  • Algorithms*
  • Computer Graphics
  • Computer Simulation
  • Computing Methodologies
  • Gene Expression Profiling / methods
  • Models, Biological*
  • Oligonucleotide Array Sequence Analysis / methods
  • Protein Interaction Mapping / methods*
  • Proteome / metabolism*
  • Signal Transduction / physiology*
  • Software*
  • User-Computer Interface*

Substances

  • Proteome