Abstract
This study aimed to assess the efficacy of surgical treatment followed by post-surgical CHOP chemotherapy and to analyze the impact of T and N stage on survival in localized intestinal diffuse large B cell lymphoma (DLBL) patients. A prospective non-randomized study was conducted and 40 patients received primary surgical resection with lymph node dissection and post-operative CHOP chemotherapy. After a median follow-up duration of 33.3 months (range, 5.1-75.9 months), an estimated 5-year overall survival rate was 88.9% and a 5-year disease-free survival rate was 83.1%. Primary surgical resection followed by post-operative CHOP chemotherapy showed high efficacy in intestinal DLBL patients.
MeSH terms
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Adult
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Aged
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Aged, 80 and over
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Combined Modality Therapy
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Cyclophosphamide / therapeutic use
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Disease-Free Survival
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Doxorubicin / therapeutic use
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Female
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Follow-Up Studies
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Humans
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Intestinal Neoplasms / diagnosis
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Intestinal Neoplasms / drug therapy*
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Intestinal Neoplasms / surgery*
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Lymphoma, B-Cell / diagnosis
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Lymphoma, B-Cell / drug therapy*
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Lymphoma, B-Cell / surgery*
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Lymphoma, Large B-Cell, Diffuse / diagnosis
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Lymphoma, Large B-Cell, Diffuse / drug therapy*
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Lymphoma, Large B-Cell, Diffuse / surgery*
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Male
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Middle Aged
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Neoplasm Staging
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Predictive Value of Tests
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Prednisolone / therapeutic use
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Prognosis
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Prospective Studies
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Survival Rate
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Treatment Outcome
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Vincristine / therapeutic use
Substances
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Vincristine
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Doxorubicin
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Cyclophosphamide
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Prednisolone