Fractal dimension in health and heart failure

Biomed Tech (Berl). 2006 Oct;51(4):194-7. doi: 10.1515/BMT.2006.035.

Abstract

Background: Non-linear analysis of heart rate variability (HRV) can give additional information about autonomic control of the heart rate. This study applied the fractal dimension (FD) in a congestive heart failure (CHF) population.

Methods: FD and HRV were evaluated in a healthy population (n=21) and an end-stage heart failure population (n=21) using 1-h segments during the day and night from Holter recordings.

Results: CHF patients presented a loss of circadian variation in both FD and conventional time- and frequency-domain HRV indices. FD was higher in the CHF population both during the day and night. In the CHF population the correlation between FD and high-frequency power of HRV was lost.

Conclusion: Day-night variations of heart rate fluctuations are lost in heart failure. Changes in FD reflecting physiological and pathophysiological changes were observed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Arrhythmias, Cardiac / diagnosis
  • Arrhythmias, Cardiac / etiology
  • Arrhythmias, Cardiac / physiopathology*
  • Biological Clocks*
  • Circadian Rhythm*
  • Diagnosis, Computer-Assisted / methods
  • Electrocardiography / methods*
  • Female
  • Fractals*
  • Heart Failure / complications
  • Heart Failure / diagnosis
  • Heart Failure / physiopathology*
  • Heart Rate*
  • Humans
  • Male
  • Middle Aged
  • Oscillometry / methods