Disseminated phaeohyphomycosis due to Ochroconis gallopavum in the setting of advanced HIV infection

Med Mycol. 2006 Dec;44(8):777-82. doi: 10.1080/13693780600900098.

Abstract

Disseminated phaeohyphomycosis is a rare and typically fatal infection caused by members of the dematiaceous fungi, and occurs almost universally in the setting of immunocompromise. We herein report a case of systemic phaeohyphomycosis caused by Ochroconis gallopavum in a patient with advanced HIV disease. A possible risk factor for this infection in our patient was heavy marijuana use. This case highlights both the diagnostic and management challenges posed by these infections. To our knowledge, this is the first reported case of disseminated phaeohyphomycosis due to Ochroconis gallopavum in a patient with HIV.

Publication types

  • Case Reports
  • Review

MeSH terms

  • AIDS-Related Opportunistic Infections / drug therapy
  • AIDS-Related Opportunistic Infections / microbiology*
  • AIDS-Related Opportunistic Infections / pathology
  • Adult
  • Antifungal Agents / administration & dosage
  • Antifungal Agents / therapeutic use
  • Ascomycota / isolation & purification*
  • Biopsy
  • Fatal Outcome
  • Histocytochemistry
  • Humans
  • Male
  • Marijuana Abuse / complications
  • Mycoses / drug therapy
  • Mycoses / microbiology*
  • Mycoses / pathology
  • Pyrimidines / administration & dosage
  • Pyrimidines / therapeutic use
  • Triazoles / administration & dosage
  • Triazoles / therapeutic use
  • Voriconazole

Substances

  • Antifungal Agents
  • Pyrimidines
  • Triazoles
  • Voriconazole