2-Pyridinone derivatives: a new class of nonnucleoside, HIV-1-specific reverse transcriptase inhibitors

J Med Chem. 1991 Sep;34(9):2922-5. doi: 10.1021/jm00113a036.

Authors

W S Saari¹, J M Hoffman, J S Wai, T E Fisher, C S Rooney, A M Smith, C M Thomas, M E Goldman, J A O'Brien, J H Nunberg, et al.

Affiliation

¹ Merck Sharp & Dohme Research Laboratories, West Point, Pennsylvania 19486-004.

PMID: 1716683
DOI: 10.1021/jm00113a036

No abstract available

MeSH terms

Antiviral Agents*
HIV-1 / enzymology*
Pyridones / pharmacology*
RNA-Directed DNA Polymerase / chemistry
RNA-Directed DNA Polymerase / pharmacology
Reverse Transcriptase Inhibitors*

Substances

Antiviral Agents
Pyridones
Reverse Transcriptase Inhibitors
2-hydroxypyridine
RNA-Directed DNA Polymerase