[Pronostic value of C-reactive protein measure in elderly patient with acquired pneumonia: correlation with Fine's score]

Rev Med Interne. 2007 Apr;28(4):213-7. doi: 10.1016/j.revmed.2006.11.015. Epub 2006 Dec 5.
[Article in French]

Abstract

The Fine's score, a predictive score of infectious pneumonia gravity, does not integrate inflammatory parameters, which are routinely used in the management of infectious pneumonia. The aim of our study was to establish a correlation between the Fine's score and C reactive protein.

Patients and methods: One hundred patients hospitalized for infectious pneumonia, 57 men and 43 female, with an average age of 85 years were retrospectively recorded.

Results: The median level of C reactive protein was 157 mg/L. Global mortality rate was 26% and respectively 5, 16 and 45% in the grades III, IV, V of the Fine's score. Beyond 75,5 mg/L C reactive protein concentration, the mortality rate was contained between 28 and 32%. The comparison of the ROC curves of the Fine's score and C reactive protein did not showed any difference.

Conclusion: C-Reactive protein is less precise than the Fine's score to assess infectious pneumonia gravity but seems to be an indicator of the potential gravity of the pneumonia.

Publication types

  • English Abstract

MeSH terms

  • Aged, 80 and over
  • C-Reactive Protein / analysis*
  • Female
  • France / epidemiology
  • Humans
  • Male
  • Pneumonia / blood*
  • Pneumonia / mortality*
  • Prognosis
  • Retrospective Studies
  • Severity of Illness Index*

Substances

  • C-Reactive Protein