There is a trade-off in neural network simulation between simulations that embody the details of neuronal biology and those that omit these details in favor of abstractions. The former approach appeals to physiologists and pharmacologists who can directly relate their experimental manipulations to parameter changes in the model. The latter approach appeals to physicists and mathematicians who seek analytic understanding of the behavior of large numbers of coupled simple units. This simplified approach is also valuable for practical reasons a highly simplified unit will run several orders of magnitude faster than a complex, biologically realistic unit. In order to have our cake and eat it, we have developed hybrid networks in the Neuron simulator package. These make use of Neuron's local variable timestep method to permit simplified integrate-and-fire units to move ahead quickly while realistic neurons in the same network are integrated slowly.