Abstract
We assessed the effect of referral bias on patients with ALS treated at our medical center. A total of 132 subjects were treated by our center over the past 3 years. The referral population had a median survival of 29 months compared to 18 months for the local population (p = 0.007). Referral bias should be addressed when assessing the efficacy of self-selected therapies in the setting of a tertiary ALS clinic.
MeSH terms
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Ambulatory Care Facilities / statistics & numerical data*
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Amyotrophic Lateral Sclerosis / mortality*
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Amyotrophic Lateral Sclerosis / nursing*
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Bias
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Cohort Studies
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Female
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Hospice Care / statistics & numerical data*
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Humans
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Male
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Middle Aged
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Patient Care Team / statistics & numerical data
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Patient Care Team / trends
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Referral and Consultation / statistics & numerical data*
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Referral and Consultation / trends
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Selection Bias
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Survival Analysis
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Survival Rate / trends