Comparison of topical anesthetics (EMLA/Oraqix vs. benzocaine) on pain experienced during palatal needle injection

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 May;103(5):e16-20. doi: 10.1016/j.tripleo.2006.11.033. Epub 2007 Feb 27.

Abstract

Objective: The aim of this study was to compare the topical anesthetic effect of 20% benzocaine gel with 2.5% lidocaine/2.5% prilocaine (L/P) cream and gel on the pain experienced during palatal anesthetic infiltration.

Study design: Two groups were studied, each containing 20 subjects. Two types of L/P mixtures were tested, an anesthetic cream (EMLA) and a thermosetting gel (Oraqix), and benzocaine was used as control. The topical agents were applied on the palatal mucosa at the canine region. A needle prick was given on each side every 2 minutes during a period of 10 minutes. The subjects recorded their findings using verbal and VAS scales.

Results: Pain scores were significantly less (P < .05) with EMLA and Oraqix than with benzocaine.

Conclusion: Topical application of EMLA and Oraqix before palatal anesthetic infiltration is associated with less pain than with benzocaine gel.

Publication types

  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Anesthesia, Dental / methods*
  • Anesthesia, Local / methods*
  • Anesthetics, Local / administration & dosage*
  • Benzocaine / administration & dosage*
  • Gels
  • Humans
  • Injections / adverse effects
  • Lidocaine / administration & dosage*
  • Lidocaine, Prilocaine Drug Combination
  • Mouth Mucosa
  • Needles / adverse effects
  • Ointments
  • Pain / etiology
  • Pain / prevention & control*
  • Pain Measurement
  • Palate, Hard
  • Prilocaine / administration & dosage*
  • Single-Blind Method

Substances

  • Anesthetics, Local
  • Gels
  • Lidocaine, Prilocaine Drug Combination
  • Ointments
  • Prilocaine
  • Lidocaine
  • Benzocaine