Abstract
This mini-review summarizes the current literature on the role of mitochondrial DNA mutations and mitochondrial metabolism in stem cell biology. The possible uses of stem cells as a therapeutic tool in mitochondrial disorders are also reported.
MeSH terms
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DNA, Mitochondrial / genetics
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Humans
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Mitochondria / physiology*
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Mitochondrial Diseases / genetics
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Mitochondrial Diseases / therapy
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Mutation
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Stem Cell Transplantation
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Stem Cells / cytology
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Stem Cells / metabolism
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Stem Cells / physiology*