The role of mitochondria in stem cell biology

Biosci Rep. 2007 Jun;27(1-3):165-71. doi: 10.1007/s10540-007-9044-1.

Abstract

This mini-review summarizes the current literature on the role of mitochondrial DNA mutations and mitochondrial metabolism in stem cell biology. The possible uses of stem cells as a therapeutic tool in mitochondrial disorders are also reported.

Publication types

  • Review

MeSH terms

  • DNA, Mitochondrial / genetics
  • Humans
  • Mitochondria / physiology*
  • Mitochondrial Diseases / genetics
  • Mitochondrial Diseases / therapy
  • Mutation
  • Stem Cell Transplantation
  • Stem Cells / cytology
  • Stem Cells / metabolism
  • Stem Cells / physiology*

Substances

  • DNA, Mitochondrial