Abstract
Alpha2-adrenergic receptor agonists exert potent analgesic and sedative/hypnotic effects. In addition, they have been shown to be neuroprotective in various experimental models, but the molecular pathways leading to these actions are still poorly defined. This review summarizes the available literature and discusses potential mechanisms of alpha2-adrenergic receptor agonist mediated neuroprotection.
Copyright (c) 2007 Prous Science. All rights reserved.
MeSH terms
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Adrenergic Agonists / pharmacokinetics
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Adrenergic Agonists / pharmacology*
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Adrenergic Agonists / therapeutic use
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Adrenergic alpha-2 Receptor Agonists*
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Animals
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Humans
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Imidazolines / pharmacokinetics
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Imidazolines / pharmacology*
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Imidazolines / therapeutic use
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Neuroprotective Agents / pharmacokinetics
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Neuroprotective Agents / pharmacology*
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Neuroprotective Agents / therapeutic use
Substances
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Adrenergic Agonists
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Adrenergic alpha-2 Receptor Agonists
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Imidazolines
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Neuroprotective Agents