Bacterial biofilm adherence to middle-ear ventilation tubes: scanning electron micrograph images and literature review

J Laryngol Otol. 2007 Oct;121(10):993-7. doi: 10.1017/S0022215107008870. Epub 2007 Jun 7.

Abstract

Introduction: The organisms that cause many device-related and other chronic infections actually grow in biofilms in or on these devices. We sought to examine the role of biofilm formation in chronic middle-ear ventilation tube infection.

Case report: Scanning electron micrograph images are presented which demonstrate biofilm on a middle-ear ventilation tube removed from a five-year-old child's chronically discharging ear. A review of the relevant international literature explores the role of biofilms in chronic infection and discusses potential intervention strategies.

Conclusion: Biofilms may be responsible for chronic middle-ear ventilation tube infection that resists treatment with conventional antibiotics.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Bacterial Adhesion / physiology
  • Biofilms / growth & development*
  • Child
  • Humans
  • Infections
  • Male
  • Microscopy, Electron, Scanning / methods*
  • Middle Ear Ventilation / instrumentation*
  • Otitis Media with Effusion / microbiology
  • Otitis Media with Effusion / surgery
  • Treatment Outcome