Chronic inflammatory demyelinating polyneuropathy in a diabetic patient: deterioration after intravenous immunoglobulins treatment and favorable response to steroid treatment

Acta Neurol Belg. 2007 Mar;107(1):14-7.

Abstract

The authors report the case of a 54-year old type-2 diabetic female patient with a Chronic Inflammatory Demyelinating Polyneuropathy (CIDP). She progressively developed distal hypoesthesia and tetraparesis. She deteriorated after two courses of intravenous immunoglobulins (IVIG) administration and became rapidly wheelchair bound. After one month of steroid treatment, the patient was walking alone. This case raises the question whether IVIG is to be considered as first line treatment for diabetes associated CIDP.

Publication types

  • Case Reports

MeSH terms

  • Azathioprine / therapeutic use
  • Diabetic Neuropathies / drug therapy
  • Diabetic Neuropathies / immunology*
  • Diabetic Neuropathies / physiopathology*
  • Disease Progression
  • Female
  • Humans
  • Immunoglobulins, Intravenous / adverse effects*
  • Methylprednisolone / therapeutic use
  • Middle Aged
  • Muscle Weakness / drug therapy
  • Muscle Weakness / immunology
  • Muscle Weakness / physiopathology
  • Peripheral Nerves / drug effects
  • Peripheral Nerves / immunology
  • Peripheral Nerves / physiopathology
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / drug therapy
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / immunology*
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / physiopathology*
  • Quadriplegia / immunology
  • Quadriplegia / physiopathology
  • Steroids / therapeutic use*
  • Treatment Outcome

Substances

  • Immunoglobulins, Intravenous
  • Steroids
  • Azathioprine
  • Methylprednisolone