Abstract
A 14-year-old girl with a Ewing's sarcoma of the left femoral head and neck is presented. The imaging features mimicked a benign cystic lesion. Biopsy and molecular analysis confirmed the diagnosis. The patient was treated with chemotherapy, wide tumor resection, and proximal femoral reconstruction using an allograft-prosthesis composite. Differential diagnosis, imaging, and pathologic features of Ewing's sarcoma are discussed.
MeSH terms
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Adolescent
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Antineoplastic Agents / therapeutic use
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Base Sequence
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Bone Neoplasms / diagnosis
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Bone Neoplasms / diagnostic imaging*
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Bone Neoplasms / drug therapy
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Bone Neoplasms / surgery
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Combined Modality Therapy
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Diagnosis, Differential
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Female
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Hip / pathology*
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Humans
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Magnetic Resonance Imaging
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Molecular Sequence Data
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Oncogene Proteins, Fusion / genetics
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Proto-Oncogene Protein c-fli-1 / genetics
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RNA-Binding Protein EWS
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Radiography
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Sarcoma, Ewing / diagnosis
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Sarcoma, Ewing / diagnostic imaging*
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Sarcoma, Ewing / drug therapy
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Sarcoma, Ewing / surgery
Substances
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Antineoplastic Agents
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EWS-FLI fusion protein
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Oncogene Proteins, Fusion
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Proto-Oncogene Protein c-fli-1
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RNA-Binding Protein EWS