Ewing's sarcoma of the hip presenting as a benign cystic lesion

J Surg Orthop Adv. 2007 Summer;16(2):84-8.

Abstract

A 14-year-old girl with a Ewing's sarcoma of the left femoral head and neck is presented. The imaging features mimicked a benign cystic lesion. Biopsy and molecular analysis confirmed the diagnosis. The patient was treated with chemotherapy, wide tumor resection, and proximal femoral reconstruction using an allograft-prosthesis composite. Differential diagnosis, imaging, and pathologic features of Ewing's sarcoma are discussed.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antineoplastic Agents / therapeutic use
  • Base Sequence
  • Bone Neoplasms / diagnosis
  • Bone Neoplasms / diagnostic imaging*
  • Bone Neoplasms / drug therapy
  • Bone Neoplasms / surgery
  • Combined Modality Therapy
  • Diagnosis, Differential
  • Female
  • Hip / pathology*
  • Humans
  • Magnetic Resonance Imaging
  • Molecular Sequence Data
  • Oncogene Proteins, Fusion / genetics
  • Proto-Oncogene Protein c-fli-1 / genetics
  • RNA-Binding Protein EWS
  • Radiography
  • Sarcoma, Ewing / diagnosis
  • Sarcoma, Ewing / diagnostic imaging*
  • Sarcoma, Ewing / drug therapy
  • Sarcoma, Ewing / surgery

Substances

  • Antineoplastic Agents
  • EWS-FLI fusion protein
  • Oncogene Proteins, Fusion
  • Proto-Oncogene Protein c-fli-1
  • RNA-Binding Protein EWS