Random subwindows and extremely randomized trees for image classification in cell biology

BMC Cell Biol. 2007 Jul 10;8 Suppl 1(Suppl 1):S2. doi: 10.1186/1471-2121-8-S1-S2.

Abstract

Background: With the improvements in biosensors and high-throughput image acquisition technologies, life science laboratories are able to perform an increasing number of experiments that involve the generation of a large amount of images at different imaging modalities/scales. It stresses the need for computer vision methods that automate image classification tasks.

Results: We illustrate the potential of our image classification method in cell biology by evaluating it on four datasets of images related to protein distributions or subcellular localizations, and red-blood cell shapes. Accuracy results are quite good without any specific pre-processing neither domain knowledge incorporation. The method is implemented in Java and available upon request for evaluation and research purpose.

Conclusion: Our method is directly applicable to any image classification problems. We foresee the use of this automatic approach as a baseline method and first try on various biological image classification problems.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Database Management Systems*
  • Erythrocytes
  • HeLa Cells
  • Humans
  • Image Interpretation, Computer-Assisted / methods*
  • Image Processing, Computer-Assisted / methods*
  • Information Storage and Retrieval
  • Observer Variation
  • Pattern Recognition, Automated*
  • Retinal Detachment
  • Software*
  • Technology