[Pharmacological treatment of Rett syndrome improves breathing and survival in a mouse model]

MeSH terms

• Adrenergic Uptake Inhibitors / pharmacology
• Adrenergic Uptake Inhibitors / therapeutic use*
• Animals
• Brain Stem / pathology
• Brain Stem / physiopathology
• Cells, Cultured / drug effects
• Cells, Cultured / metabolism
• Desipramine / pharmacology
• Desipramine / therapeutic use*
• Drug Evaluation, Preclinical
• Female
• Humans
• Methyl-CpG-Binding Protein 2 / deficiency
• Methyl-CpG-Binding Protein 2 / genetics
• Methyl-CpG-Binding Protein 2 / physiology
• Mice
• Mice, Knockout
• Nerve Tissue Proteins / deficiency
• Neurons / enzymology
• Neurons / pathology
• Norepinephrine / deficiency
• Norepinephrine / physiology
• Respiration Disorders / drug therapy*
• Respiration Disorders / etiology
• Rett Syndrome / complications
• Rett Syndrome / drug therapy*
• Rett Syndrome / genetics
• Rett Syndrome / physiopathology
• Synaptic Vesicles / drug effects
• Synaptic Vesicles / metabolism
• Tyrosine 3-Monooxygenase / deficiency