Durability of surgery for restenosis after carotid endarterectomy

J Vasc Surg. 2008 Feb;47(2):363-71. doi: 10.1016/j.jvs.2007.10.002. Epub 2007 Dec 26.

Abstract

Background: The role of carotid surgery for the management of restenosis after carotid endarterectomy (CEA) is challenged by carotid artery stenting (CAS). We reviewed redo CEA in a consecutive series of patients to determine the safety, durability, and long-term benefit associated with repeat surgical treatment for restenosis.

Methods: A consecutive series of 73 redo procedures in 72 patients (57% men) with a mean age 66 years (range, 49-81 years) was analyzed. The mean interval between prior CEA and redo CEA was 53 months (range, 8-192 months). Operative indications included symptomatic restenosis in 28 patients (38%). A patch angioplasty was performed in 62 patients (85%). The main outcome measures included perioperative and late stroke and death, and the development of secondary restenosis.

Results: There were no perioperative deaths or strokes. During a mean follow-up of 52 months (range, 12-144 months), the Kaplan-Meier cumulative survival was 85% at 5 years. At 5 years, the cumulative rate of freedom from all strokes was 98%, and the freedom from ipsilateral stroke was 100%. After secondary procedures, re-recurrent stenosis > or =50% occurred in 10 patients (13.7%). The cumulative freedom from re-restenosis (> or =50%) was 85% at 5 years. Five patients (7%) received tertiary carotid reconstructions.

Conclusion: Repeat CEA for recurrent stenosis can be performed safely with excellent long-term protection from stroke. These data provide a standard against which the results of CAS can be compared.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Carotid Stenosis / mortality
  • Carotid Stenosis / surgery*
  • Endarterectomy, Carotid / adverse effects*
  • Female
  • Follow-Up Studies
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Patient Selection
  • Recurrence
  • Registries
  • Reoperation
  • Retrospective Studies
  • Risk Assessment
  • Stroke / etiology*
  • Stroke / mortality
  • Time Factors
  • Treatment Outcome