Abstract
Background:
Two cases of conjunctival carcinoma developed orbital invasion during treatment with topical medication.
Methods:
This was a retrospective study from a tertiary ophthalmic oncology unit, performed after informed consent was obtained. The main outcome measurement was orbital invasion.
Results:
Two patients treated with topical agents developed orbital invasion.
Conclusion:
While topical agents are important in treatment of conjunctival neoplasia, recurrence or deep invasion require careful monitoring.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Administration, Topical
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Adult
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Aged
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Antimetabolites, Antineoplastic / therapeutic use*
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Carcinoma, Squamous Cell / drug therapy
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Carcinoma, Squamous Cell / secondary*
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Conjunctival Neoplasms / drug therapy
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Conjunctival Neoplasms / pathology*
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Fluorouracil / therapeutic use
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Humans
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Interferon alpha-2
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Interferon-alpha / therapeutic use
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Magnetic Resonance Imaging
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Male
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Mitomycin / therapeutic use
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Neoplasm Recurrence, Local / diagnosis*
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Orbital Neoplasms / diagnosis
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Orbital Neoplasms / secondary*
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Recombinant Proteins
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Retrospective Studies
Substances
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Antimetabolites, Antineoplastic
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Interferon alpha-2
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Interferon-alpha
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Recombinant Proteins
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Mitomycin
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Fluorouracil