Targeting skeletal muscle AMP-activated protein kinase to treat type 2 diabetes

Curr Diab Rep. 2007 Dec;7(6):399-401. doi: 10.1007/s11892-007-0065-8.

Authors

Eric B Taylor¹, Laurie J Goodyear

Affiliation

¹ The Joslin Diabetes Center and Harvard Medical School, 1 Joslin Place, Boston, MA 02215, USA. laurie.goodyear@joslin.harvard.edu

PMID: 18254999
DOI: 10.1007/s11892-007-0065-8

No abstract available

MeSH terms

AMP-Activated Protein Kinases
Aminoimidazole Carboxamide / analogs & derivatives
Aminoimidazole Carboxamide / pharmacology
Aminoimidazole Carboxamide / therapeutic use
Animals
Diabetes Mellitus, Type 2 / drug therapy*
Diabetes Mellitus, Type 2 / enzymology*
Enzyme Activation / drug effects
Enzyme Activators / pharmacology
Enzyme Activators / therapeutic use
Humans
Hypoglycemic Agents / pharmacology
Hypoglycemic Agents / therapeutic use
Mice
Multienzyme Complexes / metabolism*
Muscle, Skeletal / drug effects
Muscle, Skeletal / enzymology*
Protein Serine-Threonine Kinases / metabolism*
Protein Subunits / metabolism
Ribonucleotides / pharmacology
Ribonucleotides / therapeutic use

Substances

Enzyme Activators
Hypoglycemic Agents
Multienzyme Complexes
Protein Subunits
Ribonucleotides
Aminoimidazole Carboxamide
Protein Serine-Threonine Kinases
AMP-Activated Protein Kinases
AICA ribonucleotide