Meiotic maturation: receptor trafficking is the key

Curr Biol. 2008 May 20;18(10):R416-R418. doi: 10.1016/j.cub.2008.03.033.

Abstract

Meiotic maturation and ovulation rates in Caenorhabditis elegans are regulated by a sperm-released gradient of major sperm protein (MSP). Recent work has provided insights into the modulation of the MSP signal by the trafficking of its receptor in oocytes.

Publication types

  • Comment

MeSH terms

  • Animals
  • Caenorhabditis elegans
  • Caenorhabditis elegans Proteins / metabolism*
  • Cell Cycle Proteins / metabolism*
  • Endocytosis / physiology*
  • Female
  • Helminth Proteins / metabolism*
  • Male
  • Meiosis / physiology*
  • Oocytes / metabolism
  • Oocytes / physiology*
  • Receptor Protein-Tyrosine Kinases / metabolism*

Substances

  • Caenorhabditis elegans Proteins
  • Cell Cycle Proteins
  • Helminth Proteins
  • major sperm protein, nematode
  • Receptor Protein-Tyrosine Kinases
  • vab-1 protein, C elegans