Psychosocial outcome after extratemporal epilepsy surgery: a prospective clinical study

Turk Neurosurg. 2008 Apr;18(2):114-24.

Abstract

Aim: The purpose of this prospective clinical study was to examine the short- and long-term psychosocial outcomes of a consecutive series of patients who underwent extratemporal lobe resection due to medically-refractory epilepsy.

Materials and methods: The sample consisted of 23 consecutive patients and all patients completed a questionnaire assessing especially psychosocial outcome 6 months and 2 years after surgery. Results obtained at short- and long-term follow-ups were compared to baseline. Furthermore, the impact of seizure freedom on the psychosocial outcome was sought.

Results: The results suggested that, psychosocial outcome was improved after surgery compared to preoperative status regardless of seizure status. At long-term follow-up, significant improvements were found in social and psychological variables (p < 0.05). Levels of side effects from medication were high at long-term compared to baseline (p = 0.003). Seizure free patients showed better psychosocial outcome than those who had seizure during the postoperative period, however; only the "impact of epilepsy" scale showed significant improvement at 6 months after surgery (p = 0.02).

Conclusion: These results provide evidence that surgery caused appreciable improvements in psychosocial well-being, however; seizure freedom is not key to improving the psychosocial life of patients who have undergone extratemporal lobe epilepsy surgery.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Anticonvulsants / administration & dosage
  • Anticonvulsants / adverse effects
  • Combined Modality Therapy
  • Employment
  • Epilepsy / drug therapy
  • Epilepsy / psychology*
  • Epilepsy / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Prospective Studies
  • Psychology
  • Quality of Life*
  • Surveys and Questionnaires
  • Treatment Outcome

Substances

  • Anticonvulsants