Cryopreservation of a mother's oocytes for possible future use by her daughter with Turner syndrome: case report

Fertil Steril. 2008 Nov;90(5):2008.e9-12. doi: 10.1016/j.fertnstert.2008.05.050. Epub 2008 Aug 9.

Abstract

Objective: To report a new fertility alternative for women with Turner syndrome, who are rendered infertile, by having their mothers freeze their own oocytes for the purpose of donating to their daughters when they are adults.

Design: Case report.

Setting: Academic teaching hospital.

Patient(s): A 33-year-old healthy mother of three children; and her second child, a 6-year-old daughter recently diagnosed with Turner syndrome.

Intervention(s): Mother-to-daughter oocyte donation combined with oocyte vitrification.

Main outcome measure(s): Number of cryopreserved oocytes.

Result(s): After three cycles of ovarian stimulation, 30 oocytes were cryopreserved for the daughter's possible future use.

Conclusion(s): The treatment option presented here opens the door for the banking of a mother's oocytes as a possible donation to a young daughter with a medical condition that leads to infertility, for her possible future use.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Child
  • Cryopreservation*
  • Female
  • Fertilization in Vitro
  • Humans
  • Infertility, Female / etiology
  • Infertility, Female / therapy*
  • Oocyte Donation*
  • Oocyte Retrieval*
  • Ovulation Induction*
  • Tissue Preservation*
  • Turner Syndrome / complications*