Preoperative assessment of hilar cholangiocarcinoma using multidetector-row CT: correlation with histopathological findings

Radiat Med. 2008 Aug;26(7):402-7. doi: 10.1007/s11604-008-0249-4. Epub 2008 Sep 4.

Abstract

Purpose: Our aim was to investigate the diagnostic reliability of multidetector-row computed tomography (MDCT) for preoperative assessment of local tumoral spread in hilar cholangiocarcinoma. MATEIRALS AND METHODS: Thirteen of 30 consecutive patients with hilar cholangiocarcinoma who underwent surgery, excluding 17 patients who underwent biliary drainage or preoperative portal embolization, were retrospectively evaluated. Using MDCT systems of 4 detector rows or 16 detector rows, plain and dynamic contrast-enhanced images of three phases were obtained. Extent of tumor spread and lymph node metastasis were assessed with MDCT and compared with histopathological findings.

Results: The Bismuth-Corlette classification of hilar cholangiocarcinoma with MDCT were type I, 1 patient; type IIIa, 3 patients; type IIIb, 4 patients; and type IV, 5 patients; those with histopathological findings were type I, 1 patient; type IIIa, 2 patients; type IIIb, 4 patients; and type IV, 6 patients. One patient diagnosed as type IIIa with MDCT was pathologically diagnosed as type IV. Accuracy of MDCT in tumoral spread was 92.3%, although that of lymph node metastasis was 54%.

Conclusion: MDCT is likely to play an important role in evaluation of focal lesion spread especially in intrapancreatic tumor invasion, although a greater number of cohort cases are necessary to clearly define its role.

Publication types

  • Evaluation Study
  • Validation Study

MeSH terms

  • Aged
  • Bile Duct Neoplasms / diagnostic imaging*
  • Bile Duct Neoplasms / pathology*
  • Bile Ducts, Intrahepatic / diagnostic imaging*
  • Bile Ducts, Intrahepatic / pathology
  • Cholangiocarcinoma / diagnostic imaging*
  • Cholangiocarcinoma / pathology*
  • Contrast Media
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Male
  • Neoplasm Staging
  • Observer Variation
  • Preoperative Care / methods*
  • Radiographic Image Enhancement / methods
  • Reproducibility of Results
  • Retrospective Studies
  • Tomography, X-Ray Computed / methods*

Substances

  • Contrast Media