Abstract
A 72-year-old man receiving etanercept for the treatment of psoriatic arthritis had an exudative pleural effusion with nonspecific fluid analysis and pleural biopsy findings. He was ultimately found to have drug-induced lupus erythematosus due to the etanercept. The spectrum of autoimmune disease due to the use of tumor necrosis factor inhibitors is reviewed.
MeSH terms
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Aged
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Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
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Etanercept
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Humans
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Immunoglobulin G / adverse effects*
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Lupus Erythematosus, Systemic / chemically induced*
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Lupus Erythematosus, Systemic / diagnosis*
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Lupus Erythematosus, Systemic / therapy
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Male
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Pleural Effusion / etiology*
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Pleural Effusion / pathology
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Pleural Effusion / therapy
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Receptors, Tumor Necrosis Factor
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Immunoglobulin G
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Receptors, Tumor Necrosis Factor
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Etanercept