Abstract
Multivalent glycoconjugates were prepared using generation-4 PAMAM dendrimers, and their interaction with Langmuir monolayers containing GM3 was investigated. Excessive carbohydrate valency adversely affects the carbohydrate-carbohydrate interaction. The GM3 monolayer selectively interacts with lactose-functionalized dendrimers in the presence of calcium ions.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Carbohydrates / chemistry*
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Dendrimers / chemistry*
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G(M3) Ganglioside / chemistry*
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Glycoconjugates / chemical synthesis*
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Glycoconjugates / chemistry
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Lactose / chemistry*
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Molecular Structure
Substances
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Carbohydrates
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Dendrimers
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G(M3) Ganglioside
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Glycoconjugates
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Lactose