Schizophrenia and physical health problems

Acta Psychiatr Scand Suppl. 2009:(438):15-21. doi: 10.1111/j.1600-0447.2008.01309.x.

Abstract

Objective: To estimate the prevalence of physical health problems in patients with schizophrenia, and to appraise the impact on mortality rates and quality of life (QoL) in such patients.

Method: A selective review of clinical articles relating to physical health such as cardiovascular disease, metabolic syndrome and QoL. In addition, current guidelines and recommendations for the monitoring of physical health in schizophrenia were reviewed.

Results: Cardiovascular events contribute most strongly to the excess mortality observed in schizophrenia. Other factors that contribute significantly include obesity, metabolic aberrations, smoking, alcohol, lack of exercise and poor diet - all of which might be targets for health promoting activities.

Conclusion: Physical health problems in patients with schizophrenia are common, and contribute to the excess mortality rate, as well as decreasing QoL. Many adverse physical factors are malleable in such patients, and physical benefit may be gained by following practical guidelines for their monitoring and improvement.

Publication types

  • Review

MeSH terms

  • Alcohol Drinking / adverse effects
  • Alcohol Drinking / epidemiology
  • Antipsychotic Agents / adverse effects
  • Antipsychotic Agents / therapeutic use
  • Cause of Death
  • Chronic Disease / epidemiology*
  • Chronic Disease / mortality
  • Comorbidity
  • Exercise
  • Feeding Behavior
  • Health Behavior
  • Health Promotion
  • Health Status Indicators*
  • Humans
  • Life Style
  • Metabolic Syndrome / chemically induced
  • Metabolic Syndrome / diagnosis
  • Metabolic Syndrome / epidemiology
  • Obesity / chemically induced
  • Obesity / diagnosis
  • Obesity / epidemiology
  • Quality of Life
  • Risk Factors
  • Schizophrenia / diagnosis
  • Schizophrenia / drug therapy
  • Schizophrenia / epidemiology*
  • Schizophrenia / mortality
  • Smoking / adverse effects
  • Smoking / epidemiology

Substances

  • Antipsychotic Agents