Caught in the act: intravital multiphoton microscopy of host-pathogen interactions

Heather D Hickman; Jack R Bennink; Jonathan W Yewdell

doi:10.1016/j.chom.2008.12.007

Caught in the act: intravital multiphoton microscopy of host-pathogen interactions

Cell Host Microbe. 2009 Jan 22;5(1):13-21. doi: 10.1016/j.chom.2008.12.007.

Authors

Heather D Hickman¹, Jack R Bennink, Jonathan W Yewdell

Affiliation

¹ Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. hhickman@mail.nih.gov

Abstract

Intravital multiphoton microscopy provides a unique opportunity to discover and characterize biological phenomena in the natural context of living organisms. Here we provide an overview of multiphoton microscopy with particular attention to its application for studying host-pathogen interactions.

MeSH terms

Host-Pathogen Interactions*
Microscopy, Fluorescence, Multiphoton*
Pathology / methods*

Grants and funding

Z01 AI001053-01/ImNIH/Intramural NIH HHS/United States