Abstract
The anionic nickel(II) porphyrin NiTPPS is able to selectively sense the spermine induced left-handed Z-form of DNA while it is completely silent in the presence of right-handed B-DNA. Interactions between the DNA and the porphyrin can be easily modulated by pH and temperature. The resulting Z-DNA-porphyrin-spermine complex behaves as a supramolecular reversible information storage system and as a reversible AND logic gate.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Circular Dichroism
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DNA, Z-Form / chemistry*
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Hydrogen-Ion Concentration
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Macromolecular Substances / chemistry
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Metalloporphyrins / chemistry*
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Models, Molecular
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Nickel / chemistry
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Nucleic Acid Conformation
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Polydeoxyribonucleotides / chemistry
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Porphyrins / chemistry
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Spermine / chemistry
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Stereoisomerism
Substances
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DNA, Z-Form
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Macromolecular Substances
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Metalloporphyrins
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Polydeoxyribonucleotides
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Porphyrins
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poly(dC-dG)
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Spermine
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tetraphenylporphine sulfonate
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Nickel