Extreme pyrexia and rapid death due to Staphylococcus aureus infection: analysis of 2 cases

Clin Infect Dis. 2009 Mar 1;48(5):612-4. doi: 10.1086/597009.

Abstract

We describe unusual Staphylococcus aureus infections in 2 patients. The infections were characterized by extreme pyrexia and rapid death. Both causative organisms produced a deletion mutant form of toxic shock syndrome toxin-1 and variant enterotoxin C, which may have caused pyrexia and death.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Bacterial Toxins / genetics
  • DNA, Bacterial / genetics
  • Enterotoxins / genetics
  • Fatal Outcome
  • Female
  • Fever*
  • Humans
  • Male
  • Staphylococcal Infections / microbiology*
  • Staphylococcal Infections / physiopathology*
  • Staphylococcus aureus / genetics
  • Staphylococcus aureus / isolation & purification*
  • Superantigens / genetics

Substances

  • Bacterial Toxins
  • DNA, Bacterial
  • Enterotoxins
  • Superantigens
  • enterotoxin F, Staphylococcal
  • enterotoxin C, staphylococcal