Post-epidural headache: how late can it occur?

J Am Board Fam Med. 2009 Mar-Apr;22(2):202-5. doi: 10.3122/jabfm.2009.02.080064.

Abstract

Background: Complications of labor epidural anesthesia include a post-dural puncture headache (PDPH). A 2003 meta-analysis described the onset of PDPH as occurring from 1 to 7 days after the procedure. Presented here is the first published case of a PDPH occurring 12 days postpartum.

Methods: Twelve days after an uncomplicated labor epidural a patient was awakened by a "crushing" postural headache. The initial diagnosis was "possible subarachnoid hemorrhage." Lumbar puncture and computed tomography angiogram were normal. Despite medications a severe postural headache persisted and she was referred for an epidural blood patch. Consultants felt the headache onset after 7 days made PDPH impossible. Ultimately a delayed EBP was performed with immediate resolution of her headache.

Discussion: Meta-analyses describe that parturients have a 1.5% risk of accidental dural puncture during epidural placement. Onset of the headache occurs as early as 1 or as late as 7 days after the procedure. Epidural blood patch is the most effective treatment for PDPH and a rapid response is diagnostic.

Conclusion: Described is the first reported case of a PDPH occurring well outside the normal range of onset 1 to 7 days after epidural anesthesia. The delayed diagnosis and treatment of PDPH in this patient illustrates the limitations of over-rigorous application of pooled analyses to the care of individual patients.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anesthesia, Spinal
  • Blood Patch, Epidural
  • Female
  • Humans
  • Meta-Analysis as Topic
  • Post-Dural Puncture Headache / etiology*
  • Post-Dural Puncture Headache / physiopathology
  • Post-Dural Puncture Headache / therapy
  • Postoperative Complications
  • Spinal Puncture / adverse effects*
  • Time Factors
  • Treatment Outcome