Abstract
Castleman's disease is characterized by a non-clonal lymph node hyperplasia. Pathologically it is classified as hyaline vascular, plasmacytic, or mixed cellularity types, and clinically it may adopt a unicentric (localized) or multicentric presentation. An association of the disease with HIV infection has been found. Many uncertainties remain concerning the etiopathogenesis and the optimal treatment of this rare condition.
MeSH terms
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Angiogenesis Inhibitors / therapeutic use
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Antiviral Agents / therapeutic use
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Castleman Disease* / complications
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Castleman Disease* / epidemiology
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Castleman Disease* / pathology
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Castleman Disease* / therapy
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Female
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Glucocorticoids / therapeutic use
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HIV Infections / complications*
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Humans
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Hyalin
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Male
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Plasma Cells / pathology
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Thalidomide / therapeutic use
Substances
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Angiogenesis Inhibitors
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Antiviral Agents
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Glucocorticoids
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Thalidomide