Continuous interscalene brachial plexus block via an ultrasound-guided posterior approach: a randomized, triple-masked, placebo-controlled study

Anesth Analg. 2009 May;108(5):1688-94. doi: 10.1213/ane.0b013e318199dc86.

Abstract

Background: The posterior approach for placing continuous interscalene catheters has not been studied in a controlled investigation. In this randomized, triple-masked, placebo-controlled study, we tested the hypothesis that an ultrasound-guided continuous posterior interscalene block provides superior postoperative analgesia compared to a single-injection ropivacaine interscalene block after moderately painful shoulder surgery.

Methods: Preoperatively, subjects received a stimulating interscalene catheter using an ultrasound-guided, in-plane posterior approach. All subjects received an initial bolus of ropivacaine. Postoperatively, subjects were discharged with oral analgesics and a portable infusion device containing either ropivacaine 0.2% or normal saline programmed to deliver a perineural infusion over 2 days. The primary outcome was average pain on postoperative day (POD) 1 (scale: 0-10). Secondary outcomes included least and worst pain scores, oral opioid requirements, sleep disturbances, patient satisfaction, and incidence of complications.

Results: Of the 32 subjects enrolled, 30 perineural catheters were placed per protocol. Continuous ropivacaine perineural infusion (n = 15) produced a statistically and clinically significant reduction in average pain (median [10th-90th percentile]) on POD 1 compared with saline infusion (n = 15) after initial ropivacaine bolus (0.0 [0.0-5.0] versus 3.0 [0.0-6.0], respectively; P < 0.001). Median oral opioid consumption (oxycodone) was lower in the ropivacaine group than in the placebo group on POD 1 (P = 0.002) and POD 2 (P = 0.002). Subjects who received a ropivacaine infusion suffered fewer sleep disturbances than those in the placebo group (P = 0.005 on POD 0 and 1 nights) and rated their satisfaction with analgesia higher than subjects who received normal saline (P < 0.001).

Conclusions: Compared to a single-injection interscalene block, a 2-day continuous posterior interscalene block provides greater pain relief, minimizes supplemental opioid requirements, greatly improves sleep quality, and increases patient satisfaction after moderate-to-severe painful outpatient shoulder surgery.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Oral
  • Adult
  • Aged
  • Amides / administration & dosage*
  • Anesthetics, Local / administration & dosage*
  • Brachial Plexus / diagnostic imaging*
  • Catheters, Indwelling
  • Female
  • Humans
  • Infusion Pumps
  • Infusions, Parenteral
  • Male
  • Middle Aged
  • Narcotic Antagonists / administration & dosage
  • Nerve Block / methods*
  • Oxycodone / administration & dosage
  • Pain Measurement
  • Pain, Postoperative / prevention & control*
  • Patient Satisfaction
  • Ropivacaine
  • Shoulder / surgery*
  • Shoulder Pain / prevention & control*
  • Sleep / drug effects
  • Treatment Outcome
  • Ultrasonography, Interventional*

Substances

  • Amides
  • Anesthetics, Local
  • Narcotic Antagonists
  • Ropivacaine
  • Oxycodone