Abstract
We report a 3(1/2)-month-old infant with trisomy 21 presenting with galactorrhea in the neonatal intensive care unit (NICU). Endocrine work-up showed a high prolactin level (64.4 ng ml(-1)--normal: 0.5 to 30 ng ml(-1)). Cessation of therapy with metoclopramide (0.2 mg kg(-1) per dose q 6 h) resulted in the resolution of galactorrhea with a decrease in serum prolactin level (20.1 ng ml(-1)). We present this case to highlight this uncommon side effect of a commonly used medication in the NICU.
MeSH terms
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Abnormalities, Multiple / diagnosis
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Abnormalities, Multiple / therapy
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Down Syndrome / diagnosis
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Ductus Arteriosus, Patent / diagnosis
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Ductus Arteriosus, Patent / surgery
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Follow-Up Studies
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Galactorrhea / chemically induced*
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Galactorrhea / physiopathology
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Gastroesophageal Reflux / diagnosis
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Gastroesophageal Reflux / drug therapy*
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Humans
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Infant
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Intensive Care Units, Neonatal
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Male
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Metoclopramide / adverse effects*
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Metoclopramide / therapeutic use
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Prolactin / blood*
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Risk Assessment