Abstract
We present a convenient method to prepare fluorophores 3- or 3,7-divinyl substituted 10H-phenothiazines and their protonation forms can aggregate to become fluorescent organic nanoparticles (FONs) with bright fluorescent spots in the lysosomes of cancer cells but not normal cells.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cell Line, Tumor
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Fluorescent Dyes / metabolism*
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Humans
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Lysosomes / chemistry
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Lysosomes / metabolism*
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Microscopy, Fluorescence
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Nanoparticles / chemistry*
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Nanostructures
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Neoplasms / diagnosis
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Neoplasms / pathology*
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Phenothiazines / chemical synthesis*
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Protons
Substances
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Fluorescent Dyes
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Phenothiazines
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Protons