Cerebellar hemorrhage in a patient with propionic acidemia

Cerebellum. 2009 Sep;8(3):352-4. doi: 10.1007/s12311-009-0103-y. Epub 2009 May 26.

Abstract

Cerebellar hemorrhage (CH) is a well-known complication in newborns. Among metabolic patients, it has been classically described but rarely reported. This is the first description of a patient with propionic acidemia in whom magnetic resonance imaging (MRI) allowed diagnosis of asymptomatic CH. Due to the usual silent presentation of CH at early ages, we suggest the possibility of including a brain MRI study as part of the routine neurological evaluation in metabolic patients, especially when neurological signs appear.

Publication types

  • Case Reports

MeSH terms

  • Amino Acid Metabolism, Inborn Errors / complications*
  • Amino Acid Metabolism, Inborn Errors / metabolism*
  • Amino Acid Metabolism, Inborn Errors / pathology
  • Cerebral Hemorrhage / complications*
  • Cerebral Hemorrhage / pathology
  • Female
  • Humans
  • Infant
  • Magnetic Resonance Imaging / methods
  • Propionates / metabolism*

Substances

  • Propionates