Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors

J Med Chem. 2009 Sep 10;52(17):5271-94. doi: 10.1021/jm900552r.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents / chemistry*
  • Antineoplastic Agents / pharmacology*
  • Antineoplastic Agents / therapeutic use
  • Humans
  • Iron / chemistry
  • Iron / metabolism
  • Iron Chelating Agents / chemistry*
  • Iron Chelating Agents / pharmacology*
  • Iron Chelating Agents / therapeutic use
  • Ribonucleotide Reductases / antagonists & inhibitors*
  • Thiosemicarbazones / chemistry*
  • Thiosemicarbazones / pharmacology*
  • Thiosemicarbazones / therapeutic use

Substances

  • Antineoplastic Agents
  • Iron Chelating Agents
  • Thiosemicarbazones
  • Iron
  • Ribonucleotide Reductases