Mobilization of PML/RARalpha negative peripheral blood stem cells with a combination of G-CSF and CXCR4 blockade in relapsed acute promyelocytic leukemia pre-treated with arsenic trioxide

Haematologica. 2010 Jan;95(1):171-2. doi: 10.3324/haematol.2009.016568. Epub 2009 Oct 8.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Comment

MeSH terms

  • Adult
  • Arsenic Trioxide
  • Arsenicals / therapeutic use*
  • Combined Modality Therapy
  • Female
  • Granulocyte Colony-Stimulating Factor / antagonists & inhibitors
  • Hematopoietic Stem Cell Mobilization / methods*
  • Humans
  • Leukemia, Promyelocytic, Acute / genetics
  • Leukemia, Promyelocytic, Acute / prevention & control
  • Leukemia, Promyelocytic, Acute / therapy*
  • Nuclear Proteins / genetics
  • Oxides / therapeutic use*
  • Peripheral Blood Stem Cell Transplantation / methods*
  • Promyelocytic Leukemia Protein
  • Receptors, CXCR4 / antagonists & inhibitors
  • Receptors, Retinoic Acid / genetics
  • Retinoic Acid Receptor alpha
  • Secondary Prevention
  • Transcription Factors / genetics
  • Tumor Suppressor Proteins / genetics

Substances

  • Arsenicals
  • CXCR4 protein, human
  • Nuclear Proteins
  • Oxides
  • Promyelocytic Leukemia Protein
  • RARA protein, human
  • Receptors, CXCR4
  • Receptors, Retinoic Acid
  • Retinoic Acid Receptor alpha
  • Transcription Factors
  • Tumor Suppressor Proteins
  • Granulocyte Colony-Stimulating Factor
  • PML protein, human
  • Arsenic Trioxide