Mitochondrial proteins essential for viability mediate protein import into yeast mitochondria

Nature. 1991 Jan 17;349(6306):205-8. doi: 10.1038/349205a0.

Abstract

Only five mitochondrial proteins are known to be essential for viability of the yeast Saccharomyces cerevisiae; all of them are key components of the mitochondrial protein import system. Other components of this system are not essential for life; they include functionally redundant import receptors on the mitochondrial surface and enzymes acting upon only a few precursor proteins.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Biological Transport / genetics
  • Carrier Proteins / physiology*
  • Cell Survival / genetics
  • Fungal Proteins / metabolism
  • Mitochondria / metabolism*
  • Proteins / metabolism*
  • Saccharomyces cerevisiae / metabolism*

Substances

  • Carrier Proteins
  • Fungal Proteins
  • Proteins