Abstract
The present review gives an overview on the serotonin (5-hydroxytryptamine; 5-HT) system, its receptors and their relationship to central nervous system physiology and disorders. Additionally, we also introduce the recent knowledge about the 5-HT receptor ligands in preclinical research, clinical trials and as approved drugs.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Central Nervous System / physiology
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Central Nervous System / physiopathology
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Central Nervous System Diseases / drug therapy*
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Central Nervous System Diseases / physiopathology
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Clinical Trials as Topic
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Drug Evaluation, Preclinical
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Humans
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Ligands
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Receptors, Serotonin / drug effects
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Receptors, Serotonin / metabolism*
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Serotonin / metabolism*
Substances
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Ligands
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Receptors, Serotonin
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Serotonin