The effect of a chlorhexidine-based surgical lubricant during pelvic examination on the detection of group B Streptococcus

Am J Obstet Gynecol. 2010 Mar;202(3):276.e1-3. doi: 10.1016/j.ajog.2009.10.860. Epub 2009 Dec 22.

Abstract

Objective: The objective of the study was to estimate whether surgical lubricant used during pelvic examination alters the detection of group B Streptococcus (GBS).

Study design: We conducted a prospective cohort study of patients undergoing GBS screening at the prenatal clinics of a New York City public hospital. Two specimens were collected from each patient, before and after a pelvic examination with Surgilube (Fougera and Co, Melville, NY), a bacteriostatic surgical lubricant. Test performance indices using GBS status pre-pelvic examination as the reference were calculated.

Results: Over 10 months, 168 patients were enrolled in the study. Twenty of 168 patients (11.9%; 95% confidence interval, 7.4-17.8%) tested GBS positive before the pelvic examination. Of the initial 20 GBS-positive patients, 10 tested GBS positive after the pelvic examination with surgical lubricant. The sensitivity of detecting GBS after the examination with surgical lubricant was 50%.

Conclusion: Because pelvic examination with surgical lubricant may decrease the detection of GBS, obstetric practitioners should collect GBS screening cultures before the use of surgical lubricant.

MeSH terms

  • Adult
  • Anti-Infective Agents, Local / administration & dosage
  • Anti-Infective Agents, Local / analysis*
  • Chlorhexidine / administration & dosage
  • Chlorhexidine / analogs & derivatives*
  • Chlorhexidine / analysis
  • Female
  • Humans
  • Lubricants / administration & dosage
  • Lubricants / chemistry*
  • Physical Examination*
  • Predictive Value of Tests
  • Pregnancy
  • Prospective Studies
  • Sensitivity and Specificity
  • Streptococcal Infections / diagnosis
  • Streptococcus agalactiae / isolation & purification*
  • Vagina / microbiology*

Substances

  • Anti-Infective Agents, Local
  • Lubricants
  • chlorhexidine gluconate
  • Chlorhexidine