Easy retrieval of single amino-acid polymorphisms and phenotype information using SwissVar

Bioinformatics. 2010 Mar 15;26(6):851-2. doi: 10.1093/bioinformatics/btq028. Epub 2010 Jan 26.

Abstract

Summary: The SwissVar portal provides access to a comprehensive collection of single amino acid polymorphisms and diseases in the UniProtKB/Swiss-Prot database via a unique search engine. In particular, it gives direct access to the newly improved Swiss-Prot variant pages. The key strength of this portal is that it provides a possibility to query for similar diseases, as well as the underlying protein products and the molecular details of each variant. In the context of the recently proposed molecular view on diseases, the SwissVar portal should be in a unique position to provide valuable information for researchers and to advance research in this area.

Availability: The SwissVar portal is available at www.expasy.org/swissvar

Contact: anais.mottaz@isb-sib.ch; lina.yip@isb-sib.ch

Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Amino Acids / chemistry*
  • Databases, Protein*
  • Phenotype*
  • Polymorphism, Single Nucleotide*
  • Proteins / chemistry*
  • Proteomics / methods*

Substances

  • Amino Acids
  • Proteins