Abstract
Anti-N-methyl-D-aspartate receptor antibody has been associated with a severe stereotypic form of subacute encephalitis, often found in women with ovarian teratoma. Reported here is the diagnosis of anti-N-methyl-D-aspartate receptor encephalitis in a 5-year-old girl who presented with subacute encephalopathy and movement disorder without evidence of malignancy. Early diagnosis and treatment with immune globulin and steroids resulted in near-complete recovery.
(c) 2010 Elsevier Inc. All rights reserved.
MeSH terms
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Anti-Inflammatory Agents / therapeutic use*
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Antibodies, Anti-Idiotypic / immunology*
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Antibodies, Anti-Idiotypic / metabolism*
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Autoimmune Diseases of the Nervous System* / drug therapy
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Autoimmune Diseases of the Nervous System* / immunology
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Autoimmune Diseases of the Nervous System* / metabolism
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Child, Preschool
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Encephalitis* / drug therapy
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Encephalitis* / immunology
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Encephalitis* / metabolism
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Female
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Humans
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Methylprednisolone / therapeutic use*
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Receptors, N-Methyl-D-Aspartate / immunology*
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Receptors, N-Methyl-D-Aspartate / metabolism*
Substances
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Anti-Inflammatory Agents
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Antibodies, Anti-Idiotypic
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Receptors, N-Methyl-D-Aspartate
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Methylprednisolone