Genomic responses to abnormal gene dosage: the X chromosome improved on a common strategy

Xinxian Deng; Christine M Disteche

doi:10.1371/journal.pbio.1000318

Genomic responses to abnormal gene dosage: the X chromosome improved on a common strategy

PLoS Biol. 2010 Feb 23;8(2):e1000318. doi: 10.1371/journal.pbio.1000318.

Authors

Xinxian Deng¹, Christine M Disteche

Affiliation

¹ Department of Pathology, University of Washington, Seattle, Washington, United States of America.

Abstract

This new primer, which discusses a study by Zhang et al., provides an overview of the process by which chromosomes achieve dose compensation and the mechanisms underlying this phenomenon in Drosophila S2 cells.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Aneuploidy
Animals
Gene Dosage / genetics*
Humans
X Chromosome / genetics*

Abstract

Publication types

MeSH terms

Grants and funding