Preview. MicroRNAs: from decay to decoy

Michaela Beitzinger; Gunter Meister

doi:10.1016/j.cell.2010.02.020

Preview. MicroRNAs: from decay to decoy

Cell. 2010 Mar 5;140(5):612-4. doi: 10.1016/j.cell.2010.02.020.

Authors

Michaela Beitzinger¹, Gunter Meister

Affiliation

¹ Universität Regensburg, Universitätsstrasse 31, 93053 Regensburg, Germany.

PMID: 20211130
DOI: 10.1016/j.cell.2010.02.020

Abstract

MicroRNAs interact with Argonaute proteins to guide posttranscriptional gene silencing. Eiring et al. (2010) now show that miR-328 has a second function, acting as a decoy by binding to hnRNP E2 and lifting its translational repression of an mRNA involved in myeloid cell differentiation.

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