Progressive multifocal leukoencephalopathy in a patient with idiopathic CD4+T lymphocytopenia

Neurol India. 2010 Jan-Feb;58(1):118-21. doi: 10.4103/0028-3886.60423.

Abstract

Progressive multifocal leukoencephalopathy (PML) is demyelinating of central nervous system caused by JC virus infection and often occurs in immunodeficient individuals. We report progressive PML in a 30-year-old male with idiopathic severely depressed CD4+T lymphocyte count. He was sero-negative for human immunodeficiency virus (HIV) infection.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Astrocytes / pathology
  • CD4-Positive T-Lymphocytes / pathology*
  • HIV Infections / immunology
  • Humans
  • Leukoencephalopathy, Progressive Multifocal / complications*
  • Leukoencephalopathy, Progressive Multifocal / virology
  • Lymphopenia / etiology*
  • Lymphopenia / pathology*
  • Lymphopenia / virology
  • Magnetic Resonance Imaging / methods
  • Male
  • Oligodendroglia / pathology