Abstract
Progressive multifocal leukoencephalopathy (PML) is demyelinating of central nervous system caused by JC virus infection and often occurs in immunodeficient individuals. We report progressive PML in a 30-year-old male with idiopathic severely depressed CD4+T lymphocyte count. He was sero-negative for human immunodeficiency virus (HIV) infection.
MeSH terms
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Adult
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Astrocytes / pathology
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CD4-Positive T-Lymphocytes / pathology*
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HIV Infections / immunology
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Humans
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Leukoencephalopathy, Progressive Multifocal / complications*
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Leukoencephalopathy, Progressive Multifocal / virology
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Lymphopenia / etiology*
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Lymphopenia / pathology*
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Lymphopenia / virology
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Magnetic Resonance Imaging / methods
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Male
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Oligodendroglia / pathology