High mebendazole doses in pulmonary and hepatic hydatid disease

J Messaritakis; P Psychou; P Nicolaidou; T Karpathios; B Syriopoulou; A Fretzayas; F Krikos; N Matsaniotis

doi:10.1136/adc.66.4.532

High mebendazole doses in pulmonary and hepatic hydatid disease

Arch Dis Child. 1991 Apr;66(4):532-3. doi: 10.1136/adc.66.4.532.

Authors

J Messaritakis¹, P Psychou, P Nicolaidou, T Karpathios, B Syriopoulou, A Fretzayas, F Krikos, N Matsaniotis

Affiliation

¹ First Department of Paediatrics, Athens University School of Medicine, Aghia Sophia, Children's Hospital, Greece.

Abstract

Thirty nine children with 71 hydatid cysts were given mebendazole orally in a dose of 100-200 mg/kg/day for 12 weeks and were followed up for a mean (SD) of 63 (24) months. Twenty children (three of them after a second course) were cured and another two avoided at least one operation. No serious side effects of the drug were observed.

Publication types

Clinical Trial

MeSH terms

Administration, Oral
Adolescent
Child
Child, Preschool
Drug Administration Schedule
Echinococcosis / drug therapy*
Echinococcosis, Hepatic / drug therapy
Echinococcosis, Pulmonary / drug therapy
Female
Humans
Male
Mebendazole / administration & dosage*
Mebendazole / therapeutic use

Substances

Mebendazole