Hospital-acquired pneumonia and bacteremia caused by Legionella pneumophila in an immunocompromised patient

Infection. 2010 Apr;38(2):135-7. doi: 10.1007/s15010-009-9253-1. Epub 2010 Mar 26.

Abstract

The Legionella species is an important cause of communityand hospital-acquired pneumonia. Bacteremic pneumonia caused by L. pneumophila is rarely reported. We describe the first reported case of hospital-acquired pneumonia and bacteremia caused by L. pneumophila from Taiwan in a patient with idiopathic thrombocytopenic purpura who received steroid treatment. The patient was successfully treated with ceftazidime and clindamycin initially, followed by ciprofloxacin for 14 days. The blood isolate was further confirmed by 16S rDNA sequence analysis.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Bacteremia / diagnosis*
  • Bacteremia / drug therapy
  • Bacteremia / microbiology*
  • Ceftazidime / therapeutic use
  • Ciprofloxacin / therapeutic use
  • Clindamycin / therapeutic use
  • Cross Infection / drug therapy
  • Cross Infection / microbiology*
  • Female
  • Hospitals
  • Humans
  • Immunocompromised Host
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use
  • Legionella pneumophila / genetics
  • Legionella pneumophila / isolation & purification*
  • Legionnaires' Disease / complications*
  • Legionnaires' Disease / diagnosis*
  • Legionnaires' Disease / drug therapy
  • Legionnaires' Disease / microbiology
  • Middle Aged
  • Purpura, Thrombocytopenic, Idiopathic / complications
  • Purpura, Thrombocytopenic, Idiopathic / drug therapy
  • RNA, Bacterial / genetics
  • RNA, Ribosomal, 16S / genetics
  • Sequence Analysis, DNA
  • Steroids / adverse effects
  • Steroids / therapeutic use
  • Taiwan

Substances

  • Anti-Bacterial Agents
  • Immunosuppressive Agents
  • RNA, Bacterial
  • RNA, Ribosomal, 16S
  • Steroids
  • Clindamycin
  • Ciprofloxacin
  • Ceftazidime